HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Lawrence L Rudel Selected Research

Atherosclerosis

7/2017Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association.
11/2015New pyripyropene A derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse models.
9/2015Targeted Knockdown of Hepatic SOAT2 With Antisense Oligonucleotides Stabilizes Atherosclerotic Plaque in ApoB100-only LDLr-/- Mice.
2/2015High-oleic canola oil consumption enriches LDL particle cholesteryl oleate content and reduces LDL proteoglycan binding in humans.
10/2014Cholesterol esters (CE) derived from hepatic sterol O-acyltransferase 2 (SOAT2) are associated with more atherosclerosis than CE from intestinal SOAT2.
9/2013LDL particle core enrichment in cholesteryl oleate increases proteoglycan binding and promotes atherosclerosis.
1/2013ACAT inhibition reduces the progression of preexisting, advanced atherosclerotic mouse lesions without plaque or systemic toxicity.
5/2011Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia.
11/2010Dietary monounsaturated fatty acids appear not to provide cardioprotection.
7/2010Dietary n-3 LCPUFA from fish oil but not alpha-linolenic acid-derived LCPUFA confers atheroprotection in mice.
For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Lawrence L Rudel Research Topics

Disease

37Atherosclerosis
07/2017 - 11/2002
9Cardiovascular Diseases (Cardiovascular Disease)
07/2017 - 08/2006
9Hypercholesterolemia
11/2015 - 08/2002
7Obesity
10/2019 - 07/2007
7Hepatocellular Carcinoma (Hepatoma)
09/2014 - 09/2005
5Inflammation (Inflammations)
11/2015 - 02/2008
4Body Weight (Weight, Body)
11/2015 - 05/2005
4Coronary Disease (Coronary Heart Disease)
05/2012 - 02/2003
4Insulin Resistance
06/2010 - 07/2007
4Metabolic Syndrome (Dysmetabolic Syndrome X)
06/2010 - 09/2008
4Gallstones (Gallstone)
11/2009 - 02/2003
3Atherosclerotic Plaque (Atheroma)
09/2015 - 02/2002
3Hyperlipidemias (Hyperlipidemia)
06/2012 - 09/2008
3Hypersensitivity (Allergy)
10/2009 - 02/2008
2Non-alcoholic Fatty Liver Disease
10/2019 - 05/2010
2Type 2 Diabetes Mellitus (MODY)
01/2017 - 01/2013
2Hypertriglyceridemia
11/2014 - 04/2010
2Abdominal Obesity
09/2012 - 07/2007
1Fibrosis (Cirrhosis)
10/2019
1Alcoholic Fatty Liver
10/2019
1Liver Cirrhosis (Hepatic Cirrhosis)
10/2019
1Hepatitis
10/2019
1Wilms Tumor (Wilm's Tumor)
02/2015
1Sitosterolemia
04/2013
1Acute Coronary Syndrome
06/2012
1Coronary Artery Disease (Coronary Atherosclerosis)
06/2012
1Breast Neoplasms (Breast Cancer)
01/2011
1Dyslipidemias (Dyslipidemia)
08/2010
1Thinness
06/2010
1Tangier Disease
04/2010

Drug/Important Bio-Agent (IBA)

30CholesterolIBA
11/2015 - 08/2002
14Lipoproteins (Lipoprotein)IBA
11/2014 - 02/2003
13oxidized low density lipoproteinIBA
02/2015 - 02/2002
9LipidsIBA
10/2019 - 11/2004
9Cholesterol Esters (Cholesteryl Esters)IBA
10/2014 - 08/2002
8Sterol O-AcyltransferaseIBA
06/2012 - 08/2002
7Fatty Acids (Saturated Fatty Acids)IBA
05/2012 - 12/2004
6Antisense OligonucleotidesIBA
01/2017 - 08/2006
6ApolipoproteinsIBA
01/2013 - 02/2002
5LDL CholesterolIBA
07/2017 - 05/2007
5EnzymesIBA
01/2017 - 08/2002
5cholesteryl oleateIBA
02/2015 - 05/2007
4Dietary Fats (Dietary Fat)IBA
07/2017 - 02/2003
4Messenger RNA (mRNA)IBA
11/2015 - 02/2008
4Proteins (Proteins, Gene)FDA Link
11/2015 - 06/2008
4Monounsaturated Fatty AcidsIBA
09/2015 - 02/2003
4Apolipoprotein B-100 (Apo B 100)IBA
09/2015 - 05/2007
4LDL Receptors (LDL Receptor)IBA
10/2014 - 12/2004
4Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
01/2011 - 12/2004
4Apolipoproteins B (ApoB)IBA
04/2010 - 02/2003
4Triglycerides (Triacylglycerol)IBA
10/2007 - 02/2003
3AcyltransferasesIBA
10/2019 - 08/2006
3Sterol O-Acyltransferase 2IBA
11/2015 - 08/2006
3Oleic Acid (Oleate)IBA
02/2015 - 02/2004
3Proteoglycans (Proteoglycan)IBA
02/2015 - 01/2011
3Dietary CholesterolIBA
06/2012 - 08/2002
3Acyl Coenzyme A (Acyl CoA)IBA
05/2011 - 08/2006
3Fish OilsIBA
07/2010 - 12/2004
3Phospholipids (Phosphatides)FDA LinkGeneric
07/2010 - 12/2004
3Glucose (Dextrose)FDA LinkGeneric
06/2010 - 07/2007
3Omega-6 Fatty Acids (Omega 6 Fatty Acids)IBA
02/2009 - 02/2008
2trimethyloxamine (trimethylamine N-oxide)IBA
01/2017 - 01/2017
2dimethylaniline monooxygenase (N-oxide forming) (flavin-containing monooxygenase)IBA
01/2017 - 01/2017
21,11- O- o- methylbenzylidene- 7- O- p- cyanobenzoyl- 1,7,11- trideacetylpyripyropene AIBA
11/2015 - 11/2015
2pyripyropene AIBA
11/2015 - 05/2011
2LDL Lipoproteins (beta Lipoproteins)IBA
09/2014 - 12/2004
2HDL CholesterolIBA
09/2012 - 05/2005
2Syndecan-1 (Syndecan 1)IBA
01/2011 - 06/2008
2stearoyl-coenzyme A (stearoyl-CoA)IBA
06/2010 - 09/2008
2Trans Fatty AcidsIBA
06/2010 - 07/2007
2Stearoyl-CoA DesaturaseIBA
01/2010 - 10/2009
2Estrogens (Estrogen)FDA Link
10/2009 - 07/2007
2Toll-Like Receptor 4IBA
10/2009 - 09/2008
2Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
04/2009 - 02/2003
2FatsIBA
11/2007 - 11/2002
2HydrolasesIBA
10/2007 - 10/2003
2Apolipoproteins E (ApoE)IBA
12/2003 - 02/2003
1Unsaturated FatsIBA
07/2017
1Biological ProductsIBA
07/2017
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
02/2016
1Alanine Transaminase (SGPT)IBA
11/2015
1poststatinIBA
11/2015
1Apolipoprotein L1IBA
02/2015
1Cytosolic acetoacetyl-CoA thiolase deficiencyIBA
11/2014
1BiglycanIBA
09/2013
1Phytosterols (Plant Sterols)IBA
04/2013
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
04/2013
1Acetyl-CoA CarboxylaseIBA
01/2013
1hydroxide ionIBA
09/2012
1Calcifediol (Calcidiol)FDA Link
09/2012
1CytokinesIBA
08/2010
1alpha-Linolenic Acid (Linolenic Acid)IBA
07/2010
1Eicosapentaenoic AcidIBA
07/2010
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
06/2010
1Insulin (Novolin)FDA Link
06/2010
1Pharmaceutical PreparationsIBA
06/2010
1HDL LipoproteinsIBA
04/2010

Therapy/Procedure

3Therapeutics
06/2010 - 02/2003
1Nephrectomy
02/2015
1Glycemic Control
06/2010